OncoK9 – Case Study – Winnie | PetDx®
Case Study: Winnie - Aid-in-Diagnosis

in a Bichon with an Aggressive Bone Lesion


12-year-old | Female Spayed | Bichon Frise | 16 lbs


Use Case
  • Site Challenging to Access
Clinical Details

Winnie presented for lameness in the left hind leg. Radiographs showed an aggressive bone lesion.

Why OncoK9 Was Performed

The veterinarian suspected cancer, however the owners were hesitant to proceed with workup or referral and opted for conservative management while thinking about their options.

OncoK9 Result

Cancer Signal
Cancer Signal Detected
  • A Cancer Signal Detected result significantly increases the likelihood that cancer is present, but does not confirm the presence of cancer. This result should not be used as the sole basis for making important decisions such as treatment or euthanasia.
  • A confirmatory cancer evaluation should be performed to establish a definitive diagnosis.

Due to a Cancer Signal Detected OncoK9 result, a Confirmatory Cancer Evaluation was performed.

Confirmatory Cancer Evaluation

May include any or all of the following:

  • Thorough clinical history
  • Thorough physical exam
    • Including oral and rectal exam
  • CBC and Chemistry
  • Urinalysis
  • Thoracic radiographs – 3 views
  • Abdominal imaging – ultrasound preferred
  • Radiographs of localized areas of bone or joint pain, if present
  • Tissue sampling of any detected masses or enlarged lymph nodes for pathological analysis

In some cases, advanced imaging (such as CT and/or MRI) may be indicated.

Cancer Workup & Findings

Histopathology diagnosis: Osteosarcoma in the proximal tibia

  • Thoracic radiographs revealed no evidence of metastasis
  • At the surgical consultation, amputation was recommended
  • The owners decided to proceed with amputation

Case Takeaways

Outcome: Veterinarian

OncoK9 helped the veterinarian convince the owner to proceed with the recommended clinical management plan.

Outcome: Owner

OncoK9 helped the owner make the decision to pursue amputation. In doing so, a diagnosis was achieved and Winnie’s pain was controlled.

Outcome: Patient

Winnie’s osteosarcoma was diagnosed and she was able to start therapy. Amputation provided immediate pain relief, and also helped Winnie avoid the possibility of a painful pathologic fracture.

Case Summary

  • 12yo FS Bichon with an aggressive bone lesion
  • Owner was hesitant to pursue workup and elected conservative management while considering treatment options
  • OncoK9: Cancer Signal Detected
  • Amputation was pursued based on the OncoK9 and imaging results, which provided immediate pain relief
  • A definitive diagnosis of osteosarcoma was made

Join the Revolution in Early Cancer Detection for Dogs

If you are ready to add the OncoK9 multi-cancer early detection test to your veterinary practice, we would love to hear from you.